Pulsed Xenon UV-C disinfection mechanism

 

UV-C disinfection works according the following mechanisms;

High intensity ultraviolet light is produced by xenon flash lamps across the entire disinfecting spectrum known as UV-C. This UV-C energy passes through the cell walls of bacteria, viruses and bacterial spores. The DNA, RNA and proteins inside the micro-organisms absorb this intense UV-C energy. Xenex Full Spectrum TM UV-C (from 200 nm to 320 nm in millisecond pulses) provides four mechanisms of damage against micro-organisms.

 

 

The four types of cellular damage caused by Pulsed Xenon UV-C are:

 

Photo hydration :Pulling water molecules into the DNA that prevents transcription,

Photo splitting: Breaking the backbone of the DNA,

Photo dimerization: Improper fusing of DNA bases

All these mechanisms prevent cell replication.

 

 

Photo cross linking:

Causes cell damage and can cause cell lysis, an irreversible form of cell death.

 

 

 

 

 

 

 

 

Results

 

The PX-UV-C decontamination proved to be a valuable tool in decreasing the number of contaminations of clean rooms after regular standard operating cleaning and disinfection procedures.

Intro

 

After succesfull introduction of the Xenex Pulsed UV-C Robot in Healthcare, RevDesinfectieRobots started exploring the possibilities in the cleanroom environment.

Together with one of the Top-10 Pharmaceutical Companies of the world, after a feasibility study, the Robot was extensively tested in the challenging real life cleanroom  world of  a real life production plant over a period of more then two years. During the feasibility study more then 150 studies were run under laboratory and artificial conditions.  This study was followed by multiple application studies.

 

And the results were unexpected and amazing....parallel on the various studies, a complete Validation Package (User Requirement Specifications/Installation Qualification/Operational Qualification/Performance Qualification/Quality Assurance and Validaction/HAZOP) has been developed.

 

 

Business case

 

The occupancy rate of manufacturing cleanrooms is only increasing, due to higher efficiency demands on the production facilities. As a consequence, the pressure on the cleaning and disinfection process of cleanrooms, interior and materials, increases to fulfill the requirements of cleanliness within the manufacture facilities.  Prevention of contamination of production batches became one of the highest priorities.  More and more countries disencourage the use of chemical disinfection products. General cleaning and disinfection processes are still being influenced by the human factor.  For those reasons new automated no-touch decontamination technologies in addition to the current disinfection strategy are necessary.

RevDesinfectie Robots

Grotebrugse Grintweg 161B

4005 AE TIEL

T +31 (0) 344-627 623

F +31 (0) 344-615 080

E. info@revdesinfectierobots.nl